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Levothyroxine, also L-thyroxine or T4, is a synthetic way of the thyroid hormone thyroxine, which is normally secreted through thefollicular cells of the thyroid gland. It is also toughened to use thyroid hormone deficiency, and then to prevent the recurrence of thyroid cancer. Like its instinctively secreted counterpart, levothyroxine is chemically in the chiral L-form. The related cure dextrothyroxine (D-thyroxine) was habituated to in the quondam as a treatment as a replacement for hypercholesterolemia (exalted cholesterol levels) but was withdrawn apposite to cardiac side-effects.
Report
Thyroxine was anything else secret in pure look in 1914 at the Mayo Clinic by means of Edward Calvin Kendall from extracts of hog thyroid glands.[3 - The hormone was synthesised in 1927 by way of British chemists Charles Robert Harington and George Barger.
Medical uses
Levothyroxine is typically adapted to to treat hypothyroidism.[4 - It may also be against to action towards goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.[5 - [6 - In 1992, President George H.W. Bush told television tummler Larry Monarch that he had been prescribed levothyroxine as corner of a treatment regimen as regards Graves' contagion; the exchange was relay contemporary to satellite dish owners tracking and recording backhaul channels.[7 -
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